Paramount Pictures has released a trailer for Annihilation. The eco-thriller is an adaptation of Jeff VanderMeer’s novel and marks director and writer Alex Garland’s followup to his acclaimed directorial debut Ex-Machina.

Natalie Portman leads a cast that includes Jennifer Jason Leigh (Hateful Eight), Tessa Thompson (“Westworld”), Gina Rodriguez (Deepwater Horizon), Tuva Novotny (Possession), and Ex-Machina alumna Sonoya Mizuno and Oscar Isaac.

Annihilation follows four hot babes sent on an expedition by a mysterious group called Southern Reach to a quarantined part of the United States labeled Area X, where 11 previous missions ended with disastrous, sometimes fatal, results due to abnormal activity.

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