Teri Hatcher (“Desperate Housewives”) is set to star in Jason Mewes’ directorial debut Madness in the Method. She joins frequent Mewes collaborator Kevin Smith, Danny Trejo (Machete), Judd Nelson (Breakfast Club), Casper Van Dien (Starship Troopers), and her “Lois & Clark” co-star Dean Cain.

Madness in the Method finds Mewes playing himself and discovering he has a knack for murder while researching a role as a serial killer. No word on Hatcher’s character, but based on the film’s meta storyline, she’s probably playing herself and has burnt through her “Desperate Housewives” royalties.

Hatcher is best known for playing milfy ditz Suzanne Mayer on ABC’s “Desperate Housewives” and Lois Lane on the network’s 1993 series “Lois & Clark: The New Adventures of Superman.” She also played a memorable role as a woman with real and spectacular breasts on NBC’s “Seinfeld.”  Madness in the Method is her horror debut.