Mena Suvari, star of all things American (American Beauty, American Pie, “American Horror Story”), is set to topline Amazon Studios’ “Hysteria,” a new thriller from former pop music idol and “Invasion” and “American Gothic” creator Shaun Cassidy.

“Hysteria” finds Suvari playing an ambitious and extremely intelligent, but socially awkward, neurologist and psychiatrist at the University of Texas Medical School, who goes back home to investigate a mysterious epidemic affecting high school girls through their digital devices.

Suvari made her feature film debut in Paramount Pictures’ Kiss the Girls. Notable genre creds include Millennium Films remake of Day of the Dead, and Stuart Gordon’s Stuck, the based-on-a-true-story tale of a woman who waited for her hit-and-run victim to die in her garage while stuck on her windshield.