“Californication’s” resident lolita Madeline Zima and indie-darling Brit Marling are set to headline Jamie Babbit’s upcoming homicidal lesbian thriller Breaking the Girl. The duo play girlfriends who joke about killing off each other’s enemies up until one of them actually does.

Babbit, who helmed the underrated, so-fucked-up-it’s-awesome 2005 psych-thriller The Quiet (starring Elisha Cuthbert and Camilla Belle), is directing from a script by American Psycho and BloodRayne screenwriter Guinevere Turner.

Turner describes Breaking the Girl to After Ellen:

It’s like Wild Things if it were set in college. It’s genre-trashy fun; gratuitous girl-on-girl make-out scenes and three-inch heels.

Zima, who broke into Hollywood at the age of six in the 1992 Rebecca De Mornay thriller The Hand That Rocked the Cradle, starred in 2009’s survival-frightener The Collector. She is best known, however, for her roles as sexy teen plagiarist Mia Lewis on Showtime’s “Californication” and Gretchen Berg, Hayden Panettiere’s bisexual roommate, on NBC’s “Heroes.”

Brit Marling will soon be seen in Fox Searchlight’s thoughtful sci-fi drama Another Earth. The film, which revolves around the discovery of a duplicate planet Earth, won the Special Jury Prize at this year’s Sundance Film Festival.